Septicaemia and meningitis caused by dysgonic fermenter-2 (DF-2).
نویسندگان
چکیده
A patient developed dysgonic fermenter-2 (DF-2) septicaemia and meningitis after having been bitten by a dog. The pathogenic organism was isolated from the oral cavity of the dog, which, it is believed, is the first time that this has been done. The growth characteristics of the organism and the immunological response of the patient were studied. The isolation of the infecting agent from the dog confirms that the oropharyngeal flora of dogs is a reservoir of the organism: the fastidiousness and slow growth of this Gram negative bacillus may account for the small number of reported cases of infection caused by this organism.
منابع مشابه
Septicaemia with a dysgonic fermenter-2 (DF-2) bacterium in a compromised host.
Dysgonic fermenter-2 (DF-2) is a newly described gram-negative bacterium that can produce serious infections in the compromised host. We are reporting a case of DF-2 septicaemia in a splenectomized patient with chronic lymphocytic leukaemia. The clinical spectrum of infections due to the DF-2 bacterium, the difficulties in establishing the diagnosis and the preferential treatment are discussed.
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A case of Waterhouse-Friderichsen syndrome associated with septicaemia caused by a DF-2 group bacterium (dysgonic fermenter--type 2--Atlanta classification) is presented. Attention is drawn to the relation of DF-2 group septicaemias to dog bites (or contact) and impaired host defence after splenectomy.
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The dysgonic fermenter-2 bacterium is a newly recognized fastidious gram-negative bacillus that causes bacteremia and sometimes endocarditis in immunocompromised persons after they are bitten by dogs. To develop an experimental model of this infection, we placed polyethylene catheters across the aortic valves of New Zealand white rabbits, which were inoculated intravenously the next day with dy...
متن کاملSusceptibility of dysgonic fermenter 2 to antimicrobial agents in vitro.
Dysgonic fermenter 2 (DF-2) is a fastidious, gram-negative organism well recognized as a cause of fulminant septicemia in patients without spleens or patients with alcoholic cirrhosis. In vitro antibiotic susceptibility testing of eight strains with a Schaedler broth dilution technique revealed DF-2 to be susceptible to all of the antibiotics tested except aztreonam. Previous reports that DF-2 ...
متن کاملEvidence for a feline reservoir for dysgonic fermenter 2 keratitis.
A 78-year-old female developed microbial keratitis from which corneal scrapings grew dysgonic fermenter 2. The infection initially responded poorly to a combination of topical antibiotics and corticosteroids but healed with intensive antibiotic therapy. There was no systemic predisposition to infection, and only feline exposure had occurred. Close association with a cat probably contaminated th...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 39 9 شماره
صفحات -
تاریخ انتشار 1986